Here, we demonstrate that conolidine, a pure analgesic alkaloid used in standard Chinese drugs, targets ACKR3, thus providing additional proof of a correlation concerning ACKR3 and discomfort modulation and opening different therapeutic avenues with the remedy of chronic agony. Though this research identifies the correlation concerning conolidine and ACKR3, https://www.proleviate.com/post/conolidine-proleviate-for-pain-muscle-joint-ankle-relief