Conolidine’s analgesic results stem from its conversation with non-opioid pain pathways. Compared with opioids, which bind to µ-opioid receptors during the central nervous procedure, conolidine modulates alternate molecular targets. A Science Advances research found that conolidine interacts With all the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availabil... https://rafaelnngcu.ourcodeblog.com/38761015/a-review-of-alternative-natural-pain-relief-to-replace-traditional-painkillers