USP3 and PIC/S5 listing additional things to generally be concluded within the OQ which includes cleaning and leak tests. Decontamination cycle improvement happens following the completion with the OQ which is talked over in detail in segment 6. The mixing of VHP sterilization inside of OEB4 and OEB5 isolators https://vhp-sterilization47024.yourkwikimage.com/2200830/vhp_sterilization_of_isolators_fundamentals_explained